3d printing for rapid prototyping of microfluidic chips: microfluidics is a fast-growing field showing great potential for a wide range of applications.
Prototyping of micro-fluid devices presents many challenges.
Manufacturing technology such as clean room
Processes based on micro-manufacturing, injection molding, milling and bonding are usually slow and expensive, and conventional 3D printers do not produce fluid-
A sealing device capable of responding to the required high pressure.
In addition, traditional 3D printing materials are not suitable for micro-fluid applications because they are not chemical or biological compatible and opaque.
So far, this has prevented the application of 3D printing technology in micro-fluid applications.
Micro-fluid is a fast
The growing field shows great potential for a wide range of applications, including point-of-
Medical diagnosis, analysis, drug development, organs-on-a-
Chip, education, chemical synthesis and biomedical analysis, as well as research and development.
Obviously, it is necessary to supplement the existing microfluid device production technology in a faster and more economical way
Effective 3D printing technology to create fluid-
Sealing device capable of withstand high pressure used in many applications.
Traditionally, the choice and challenge of using clean room to produce prototype micro-fluid devices
Based on micro-manufacturing technologies such as flat printing.
While these products are very accurate and able to deliver the highest possible quality, they are also very expensive and slow.
An alternative technology developed by white people in the 1990 s.
Sides research group at Harvard University, allowing micron-
Proportional features replicated by casting polyzhengdione-Silicone rubber (PDMS)
, Create an open channel and then have to be closed with the lid.
This method has become a pillar of the academic research of microfluid.
3D printing technology is attractive in nature because it can theoretically copy the design very quickly and economically, however, traditional 3D printers are not designed for micro-fluid applications, which brings some
These printers use stereo exposure (SLA)
Selective Laser Sintering (SLS)
And a model of molten deposition (FDM)
These techniques often fail to work effectively, either because they use the wrong material type or because they cause internal gaps to be filled with supporting materials.
Difficulties in printing hollow structure-
For example, a micro-fluid chip with a micro-distorted channel-
It folds when the lid is printed because it has no support.
SLA and SLS technology through UV-
Cured photo polymer and powder polymer, but the material used cannot be removed from the micro-fluid channel afterwards.
Although support materials may not be used in some cases, support materials may also be required for FDM technology.
Safety of fluid-
The path of the seal cannot be guaranteed, in addition, UV-
The solidified photo polymer used in the SLA does not represent the material used in biological applications.
So far, there is no 3D printer designed specifically for fluid manufacturing. sealed devices.
For most applications, the main function of a 3D printer is to create a prototype device, such as a mobile phone, where the priority is the appearance.
In the micro-fluid, the opposite is true;
The most important consideration is the channel structure inside the micro-flow control chip.
Fluid plant recently launched-
The first commercial 3D printer for fluidsealed devices--
Solve this shortcoming.
It uses a finite difference technique to melt the fibers of a given polymer and deposit them in layers to build a model.
It\'s a quick, cost-
Effective technology is ideal for prototyping and has been carefully designed to avoid the need for supporting materials during printing.
This is also the first 3D printer to hold a ring olefin polymer (COC), an FDA-
The approved material has many advantages over other polymers.
The material is transparent, chemical and biocompatible, does not automatically fluorescent and absorbs very low water.
Traditional 3D printers compromise in the internal form, because the materials used are usually opaque, so the internal form is usually invisible.
However, the fluid plant works from inside to outside, but focuses on the internal structure to ensure the precise geometry of the micro-fluid channel;
Appearance is a secondary consideration.
Most FDM printers work by heating the polymer until it melts and then spraying the polymer in the form of a circular cross
Some of the solidified beads.
However, space is reserved between beads, forming a leak path (Figure 1).
The fluid factory overcomes this problem by assigning beads with a \"squeeze\" crosssectional area.
When printing more layers, the polymer flows seamlessly into the area above and below these beads to ensure reliable leakage
Free sealing of fluid channels (Figure 1). This one-
Step process is a significant advantage that allows the creation of accurate circular, triangular, or rectangular channel geometry-
Various functions cannot be achieved using etching, stamping, molding or processing techniques.
A wide range of equipment can be produced in this way, including droplets and emulsion chips, micromixers, microreactors, connectors, custom fluid manifold, sensor boxes, valves and medical equipment.
The open format print file is downloaded from the system\'s design library, or a custom design created using CAD software and uploaded to the printer via a USB connection, allowing the generation of structures of any shape and geometry.
This makes it simple, cost-
Effectively produce a single micro-fluid device that allows for temporary changes to the structural design and geometry and is easy to reprint the device.
Abstract: This time, a 3D printer designed for fluid is launched.
The sealing device is an important step forward in the development of micro-fluid technology, which provides fast, reliable and cost-effective-
Print effectively.
This is ideal for testing specific concepts for the production of a small number of prototype equipment, complementing traditional manufacturing techniques such as injection molding and Micro
Grinding and bonding.
This fast, cost-effective single prototype manufacturing improves the development speed of micro-fluid devices for mass production
Benefit the industry by helping to shorten time to market and expand manufacturing processes. --Omar Jina, Ph.
Title: Baiyun microfluid fluid factory is the first commercial 3D printer available for fluidsealed devices.
Source: Baiyun micro-fluid description: Selection of micro-fluid chips manufactured by the 3D printer of the fluid plant.
Title: fluid factory 3D printer use fast, cost-
Effective technology is ideal for prototyping and has been carefully designed to avoid the need for supporting materials during printing.
Image source: Baiyun micro-fluid description: Figure 1: Finite difference printing technology: Circular Crosssection bead (left)
There\'s also a crossroads. section bead (right).
Manufacturing technology such as clean room
Processes based on micro-manufacturing, injection molding, milling and bonding are usually slow and expensive, and conventional 3D printers do not produce fluid-
A sealing device capable of responding to the required high pressure.
In addition, traditional 3D printing materials are not suitable for micro-fluid applications because they are not chemical or biological compatible and opaque.
So far, this has prevented the application of 3D printing technology in micro-fluid applications.
Micro-fluid is a fast
The growing field shows great potential for a wide range of applications, including point-of-
Medical diagnosis, analysis, drug development, organs-on-a-
Chip, education, chemical synthesis and biomedical analysis, as well as research and development.
Obviously, it is necessary to supplement the existing microfluid device production technology in a faster and more economical way
Effective 3D printing technology to create fluid-
Sealing device capable of withstand high pressure used in many applications.
Traditionally, the choice and challenge of using clean room to produce prototype micro-fluid devices
Based on micro-manufacturing technologies such as flat printing.
While these products are very accurate and able to deliver the highest possible quality, they are also very expensive and slow.
An alternative technology developed by white people in the 1990 s.
Sides research group at Harvard University, allowing micron-
Proportional features replicated by casting polyzhengdione-Silicone rubber (PDMS)
, Create an open channel and then have to be closed with the lid.
This method has become a pillar of the academic research of microfluid.
3D printing technology is attractive in nature because it can theoretically copy the design very quickly and economically, however, traditional 3D printers are not designed for micro-fluid applications, which brings some
These printers use stereo exposure (SLA)
Selective Laser Sintering (SLS)
And a model of molten deposition (FDM)
These techniques often fail to work effectively, either because they use the wrong material type or because they cause internal gaps to be filled with supporting materials.
Difficulties in printing hollow structure-
For example, a micro-fluid chip with a micro-distorted channel-
It folds when the lid is printed because it has no support.
SLA and SLS technology through UV-
Cured photo polymer and powder polymer, but the material used cannot be removed from the micro-fluid channel afterwards.
Although support materials may not be used in some cases, support materials may also be required for FDM technology.
Safety of fluid-
The path of the seal cannot be guaranteed, in addition, UV-
The solidified photo polymer used in the SLA does not represent the material used in biological applications.
So far, there is no 3D printer designed specifically for fluid manufacturing. sealed devices.
For most applications, the main function of a 3D printer is to create a prototype device, such as a mobile phone, where the priority is the appearance.
In the micro-fluid, the opposite is true;
The most important consideration is the channel structure inside the micro-flow control chip.
Fluid plant recently launched-
The first commercial 3D printer for fluidsealed devices--
Solve this shortcoming.
It uses a finite difference technique to melt the fibers of a given polymer and deposit them in layers to build a model.
It\'s a quick, cost-
Effective technology is ideal for prototyping and has been carefully designed to avoid the need for supporting materials during printing.
This is also the first 3D printer to hold a ring olefin polymer (COC), an FDA-
The approved material has many advantages over other polymers.
The material is transparent, chemical and biocompatible, does not automatically fluorescent and absorbs very low water.
Traditional 3D printers compromise in the internal form, because the materials used are usually opaque, so the internal form is usually invisible.
However, the fluid plant works from inside to outside, but focuses on the internal structure to ensure the precise geometry of the micro-fluid channel;
Appearance is a secondary consideration.
Most FDM printers work by heating the polymer until it melts and then spraying the polymer in the form of a circular cross
Some of the solidified beads.
However, space is reserved between beads, forming a leak path (Figure 1).
The fluid factory overcomes this problem by assigning beads with a \"squeeze\" crosssectional area.
When printing more layers, the polymer flows seamlessly into the area above and below these beads to ensure reliable leakage
Free sealing of fluid channels (Figure 1). This one-
Step process is a significant advantage that allows the creation of accurate circular, triangular, or rectangular channel geometry-
Various functions cannot be achieved using etching, stamping, molding or processing techniques.
A wide range of equipment can be produced in this way, including droplets and emulsion chips, micromixers, microreactors, connectors, custom fluid manifold, sensor boxes, valves and medical equipment.
The open format print file is downloaded from the system\'s design library, or a custom design created using CAD software and uploaded to the printer via a USB connection, allowing the generation of structures of any shape and geometry.
This makes it simple, cost-
Effectively produce a single micro-fluid device that allows for temporary changes to the structural design and geometry and is easy to reprint the device.
Abstract: This time, a 3D printer designed for fluid is launched.
The sealing device is an important step forward in the development of micro-fluid technology, which provides fast, reliable and cost-effective-
Print effectively.
This is ideal for testing specific concepts for the production of a small number of prototype equipment, complementing traditional manufacturing techniques such as injection molding and Micro
Grinding and bonding.
This fast, cost-effective single prototype manufacturing improves the development speed of micro-fluid devices for mass production
Benefit the industry by helping to shorten time to market and expand manufacturing processes. --Omar Jina, Ph.
Title: Baiyun microfluid fluid factory is the first commercial 3D printer available for fluidsealed devices.
Source: Baiyun micro-fluid description: Selection of micro-fluid chips manufactured by the 3D printer of the fluid plant.
Title: fluid factory 3D printer use fast, cost-
Effective technology is ideal for prototyping and has been carefully designed to avoid the need for supporting materials during printing.
Image source: Baiyun micro-fluid description: Figure 1: Finite difference printing technology: Circular Crosssection bead (left)
There\'s also a crossroads. section bead (right).
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